Document Detail

Toxicity of dimethoate and fenoxycarb to honey bee brood (Apis mellifera), using a new in vitro standardized feeding method.
MedLine Citation:
PMID:  17879979     Owner:  NLM     Status:  MEDLINE    
A new in vitro method was devised to assess the effects of pesticides on honey bee brood. The method allowed the quantification of doses ingested by larvae and the assessment of larval and pupal mortality. Larval mortality in control samples was lower than 10%. Two active substances were tested: dimethoate and fenoxycarb. The LD(50) of dimethoate was 1.9 microg larva(-1) 48 h after oral exposure of larvae at day 4. Additional dose-related effects on pupal mortality were noted. After a chronic intoxication, the NOAEC (No Observed Adverse Effect Concentration) for larval mortality at day 7 was 2.5 mg kg(-1), whereas a NOAEC of 5 mg kg(-1) was found at day 22 for delayed effects on the reduction of adult emergence. Fenoxycarb applied at day 4 showed no effect on larvae, whereas emergence of adults was affected at doses higher than 6 ng larva(-1).
Pierrick Aupinel; Dominique Fortini; Bruno Michaud; Franck Marolleau; Jean-Noël Tasei; Jean-François Odoux
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pest management science     Volume:  63     ISSN:  1526-498X     ISO Abbreviation:  Pest Manag. Sci.     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-15     Completed Date:  2008-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100898744     Medline TA:  Pest Manag Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  1090-4     Citation Subset:  IM    
Unité Expérimentale d'Entomologie INRA Le Magneraud, BP 52-17700, Surgères, France.
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MeSH Terms
Acute Toxicity Tests / methods
Bees / drug effects*,  growth & development
Dimethoate / toxicity*
Insecticides / toxicity*
Larva / drug effects
Phenylcarbamates / toxicity*
Toxicity Tests / methods*
Toxicity Tests, Chronic / methods
Reg. No./Substance:
0/Insecticides; 0/Phenylcarbamates; 60-51-5/Dimethoate; 72490-01-8/fenoxycarb

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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