Document Detail

Toxicity of a commercial herbicide containing terbutryn and triasulfuron to seabream (Sparus aurata L.) larvae: a comparison with the Microtox test.
MedLine Citation:
PMID:  15327877     Owner:  NLM     Status:  MEDLINE    
The present study aimed to compare the sensitivity of larvae of the gilthead seabream (Sparus aurata), a valuable fish species of the Spanish South Atlantic littoral, with the extensively used Microtox test on a commercial herbicide formulation containing terbutryn (59.4%) and triasulfuron (0.6%). To this purpose, mortality displayed by endogenous feeding S. aurata larvae exposed during 72 h post-hatching to nominal concentrations of the commercial formulation and bioluminescence of the marine bacterium Vibrio fischeri were compared. Histomorphological changes were also studied. Clearly, the S. aurata assay was the more sensitive indicator of toxicity for this herbicide. The 72-h concentration lethal to 50% of the individuals (LC(50)) found for yolk sac larvae was 1.41 mg/L. This value was more than one order of magnitude below the 15-min EC(50) found for V. fischeri (15.94 mg/L). Growth of the larvae was not significantly affected by a terbutryn-triasulfuron mixture at concentrations up to 1.56 mg/L, the maximum at which there was some proportion of survival.
Maria I Arufe; J Arellano; M J Moreno; C Sarasquete
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ecotoxicology and environmental safety     Volume:  59     ISSN:  0147-6513     ISO Abbreviation:  Ecotoxicol. Environ. Saf.     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-08-25     Completed Date:  2005-01-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7805381     Medline TA:  Ecotoxicol Environ Saf     Country:  United States    
Other Details:
Languages:  eng     Pagination:  209-16     Citation Subset:  IM    
Department of Toxicology, Medicine Faculty, University of Cádiz, Cádiz 11003, Spain.
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MeSH Terms
Herbicides / toxicity*
Histological Techniques
Larva / drug effects,  growth & development
Lethal Dose 50
Luminescent Measurements
Sea Bream / growth & development*
Sulfonylurea Compounds / toxicity*
Triazines / toxicity*
Vibrio fischeri / drug effects*,  metabolism
Reg. No./Substance:
0/Herbicides; 0/Sulfonylurea Compounds; 0/Triazines; 82097-50-5/triasulfuron; 886-50-0/terbutryne

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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