| Toxicity of cadmium and zinc mixtures to the decaudized cercarial life span of Diplostomum spathaceum. | |
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MedLine Citation:
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PMID: 16336720 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of cadmium and zinc mixtures at concentrations ranging from 0.1 to 10,000 microg l(-1) on the life-span of decaudized cercarial bodies (cercariae that have shed their tails) of Diplostomum spathaceum (Trematoda: Diplostomatidae) was investigated. Cercariae were exposed to metal mixtures of equal and unequal concentrations, and a low-dose pre-treatment followed by a high-dose exposure mixtures. Metal mixtures demonstrated variable effects on decaudized cercariae either by increasing or reducing their life-span compared to single metal exposures dependent on concentration and the type of mixed metal treatment. Prolonged exposure to equal metal mixtures at low concentrations (0.1-100 microg l(-1)) resulted in a reduction in the life-span of decaudized cercariae at 0.1 and 100 microg l(-1) in those individuals decaudized during the initial 24 h exposure period compared with those decaudized during the final 24 h period of cercarial survival, whilst in controls there was no significant life-span change between the two time periods. Decaudized cercariae which were exposed to low concentrations (0.1-100 microg l(-1)) of equal metal mixtures were also evaluated for their role as an indicator of larval 'fitness' for migrating through the tissues of their target fish host for those individuals decaudized during the initial 24 h exposure period, and demonstrated only a limited change in their life-span compared to control and single metal exposures. The importance of metal mixtures in parasite establishment in the fish host is discussed. |
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Authors:
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N J Morley; M Crane; J W Lewis |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of helminthology Volume: 79 ISSN: 0022-149X ISO Abbreviation: J. Helminthol. Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2005-12-12 Completed Date: 2006-04-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985115R Medline TA: J Helminthol Country: England |
Other Details:
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Languages: eng Pagination: 353-9 Citation Subset: IM |
Affiliation:
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School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK. n.morley@rhul.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antiparasitic Agents / pharmacology* Cadmium / toxicity* Dose-Response Relationship, Drug Life Cycle Stages Parasitic Sensitivity Tests Trematoda / drug effects*, physiology Zinc / toxicity* |
| Chemical | |
Reg. No./Substance:
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0/Antiparasitic Agents; 7440-43-9/Cadmium; 7440-66-6/Zinc |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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