Document Detail


Toxicity and biodegradation of diamines.
MedLine Citation:
PMID:  11990359     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Phytotoxicity and cytotoxicity of 2,4-diaminotoluene (2,4-D), 4,4'-methylenedianiline (4,4-D), and 1,6-hexanediamine (1,6-D) were investigated by observing the germination of young radish seeds and the viability of HeLa cells, respectively. 2,4-D showed the highest, 4,4-D intermediate, and 1,6-D lowest cytotoxicity. However, the phytotoxicity decreased in the order of 4,4-D > 2,4-D > 1,6-D. Contrary to the results previously reported, in the modified Sturm test the activated sludge degraded 2,4-D and 4,4-D as well as 1,6-D without any pre-acclimation. Ochrobacterium antropi was isolated for degradation of 2,4-D and 4,4-D and Pseudomonas citronellolis for 1,6-D degradation. Thielevia sp. was isolated as 2,4-D degrading fungus and Aspergillus sp. as 4,4-D and 1,6-D degrading fungus. The fungi degraded the diamines faster than the bacteria.
Authors:
Mal-Nam Kim; Ji-Chul Jang; Ik-Mo Lee; Han-Sup Lee; Jin-San Yoon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes     Volume:  37     ISSN:  0360-1234     ISO Abbreviation:  J Environ Sci Health B     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-05-06     Completed Date:  2002-12-12     Revised Date:  2009-07-21    
Medline Journal Info:
Nlm Unique ID:  7607167     Medline TA:  J Environ Sci Health B     Country:  United States    
Other Details:
Languages:  eng     Pagination:  53-64     Citation Subset:  IM    
Affiliation:
Department of Biology, Sangmyung University, Seoul, Korea. mnkim@sangmyung.ac.kr
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MeSH Terms
Descriptor/Qualifier:
Aniline Compounds / metabolism,  toxicity
Aspergillus / isolation & purification,  metabolism*
Biodegradation, Environmental
Cell Survival / drug effects
Diamines / metabolism*,  toxicity*
Germination / drug effects
Hela Cells
Humans
Ochrobactrum anthropi / isolation & purification,  metabolism*
Phenylenediamines / metabolism,  toxicity
Pseudomonas / isolation & purification,  metabolism*
Raphanus / drug effects,  physiology
Seeds / drug effects,  physiology
Toxicity Tests
Chemical
Reg. No./Substance:
0/Aniline Compounds; 0/Diamines; 0/Phenylenediamines; 101-77-9/4,4'-diaminodiphenylmethane; 124-09-4/1,6-diaminohexane; 95-80-7/2,4-diaminotoluene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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