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Toxicity of aqueous C(70) -gallic acid suspension in Daphnia magna.
MedLine Citation:
PMID:  22038846     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The present study assessed the toxic effects of stable aqueous colloidal suspensions of gallic acid stabilized C(70) -fullerene to Daphnia magna. The suspensions were stabilized through non-covalent surface modification with gallic acid. In addition to whole organism responses, changes in antioxidative processes in D. magna were quantified. Acute toxicity was observed with 96LC50 for C(70) -gallic acid of 0.4 ± 0.1 mg/L C(70) . Daphnia magna fecundity was significantly reduced in 21d bioassays at C(70) -gallic concentrations below quantifiable limits. Antioxidant enzyme activities of glutathione peroxidase and superoxide dismutase as well as lipid peroxidation suggested that exposed organisms experienced oxidative stress. Microscopy techniques used to determine cellular toxicity via apoptosis proved unsuccessful. Environ. Toxicol. Chem. © 2011 SETAC.
Authors:
Brandon C Seda; Pu-Chun Ke; Andrew S Mount; Stephen J Klaine
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-28
Journal Detail:
Title:  Environmental toxicology and chemistry / SETAC     Volume:  -     ISSN:  1552-8618     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308958     Medline TA:  Environ Toxicol Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 SETAC.
Affiliation:
Institute of Environmental Toxicology, Clemson University, Pendleton, South Carolina, USA. bseda@clemson.edu.
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