Document Detail


Toxicity and anticoagulant activity of Salvia splendens.
MedLine Citation:
PMID:  16414649     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Toxicological studies carried out on aqueous extract of Salvia splendens commonly known as Red Sage reveals that the drug is toxic only in higher doses and causes hemorrhages. LD50 of S. splendens is 1287.3 mg/Kg. Salvia splendens possesses anticoagulant property. The aqueous root extract of Salvia splendens increases the clotting time of dog's plasma by increasing the normal prothrombin time from 10-15 seconds to 35 seconds. Furthermore, the anticoagulant activity depends upon the part of the plant i.e. flowers, aerial parts and roots.
Authors:
I H Qureshi; S Ahmad; Z Kapadia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pakistan journal of pharmaceutical sciences     Volume:  2     ISSN:  1011-601X     ISO Abbreviation:  Pak J Pharm Sci     Publication Date:  1989 Jul 
Date Detail:
Created Date:  2006-01-17     Completed Date:  2006-02-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426356     Medline TA:  Pak J Pharm Sci     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  75-9     Citation Subset:  -    
Affiliation:
Pharmaceutical and Fine Chemical Division, P.C.S.I.R. Laboratory, Karachi-39, Pakistan.
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