Document Detail


Toxicity of Diplodia maydis to laboratory animals.
MedLine Citation:
PMID:  410365     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ten strains of Diplodia maydis isolated from commercial corn samples and grown on whole yellow corn at 25 degrees C for 6 weeks were toxic to ducklings and rats. The degree of toxicity depended on the incubation period and temperature. Minimum incubation periods of 3 to 4 weeks and 6 weeks were necessary to cause mortality in ducklings and rats, respectively. Cultures incubated at 31 and 25 degrees C were much more toxic than those kept at 16 and 20 degrees C. Heat treatments at 80 to 90 degrees C destroyed most of the toxicity of moldy meal. Mild lesions of a similar histopathological nature were found in subclinically and lethally poisoned rats. These included toxic myocarditis, enteritis, focal renal tubular necrosis, degeneration and peripheral necrosis of the islets of Langerhans, and a generalized venous congestion.
Authors:
C J Rabie; S J van Rensburg; N P Kriek; A Lübben
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  34     ISSN:  0099-2240     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-11-25     Completed Date:  1977-11-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  111-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animal Feed
Animals
Ducks
Haplorhini
Mitosporic Fungi* / growth & development
Mycotoxins / toxicity*
Papio
Rats
Temperature
Zea mays / microbiology
Chemical
Reg. No./Substance:
0/Mycotoxins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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