Document Detail

Toxic methaemoglobin concentrations in premature infants after application of a prilocaine-containing cream and peridural prilocaine.
MedLine Citation:
PMID:  10486075     Owner:  NLM     Status:  MEDLINE    
CONCLUSION: Whereas local skin application of prilocaine to premature babies is safe, peridural administration is not because premature infants are more sensitive to methaemoglobin inducing agents and tolerate methaemoglobinaemia less well.
B Frey; B Kehrer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  158     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-11-17     Completed Date:  1999-11-17     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  785-8     Citation Subset:  IM    
Intensive Care Unit, Ostschweizer Kinderspital, CH-9006 St Gallen, Switzerland.
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MeSH Terms
Anesthesia, Caudal / adverse effects*
Anesthetics, Local / adverse effects*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / chemically induced*
Lidocaine / adverse effects*
Methemoglobinemia / chemically induced*,  diagnosis
Prilocaine / administration & dosage,  adverse effects*
Retrospective Studies
Time Factors
Reg. No./Substance:
0/Anesthetics, Local; 0/EMLA; 137-58-6/Lidocaine; 721-50-6/Prilocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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