Document Detail


Toxic leukoencephalopathy due to transdermal fentanyl overdose.
MedLine Citation:
PMID:  21926884     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Children with altered mental status who present to the emergency department have a broad differential diagnosis. We report a case of a 19-month-old girl who presented in coma and who was later found to have a fentanyl patch adhered to her back. She was found to have changes on brain magnetic resonance imaging consistent with a toxic spongiform leukoencephalopathy but had a good neurologic outcome. This case report illustrates the importance of a thorough physical examination in children in coma and a rarely reported magnetic resonance imaging finding that has been seen in opioid intoxication and is usually associated with severe morbidity and mortality.
Authors:
Lindsey Foy; Desiree M Seeyave; Stuart A Bradin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric emergency care     Volume:  27     ISSN:  1535-1815     ISO Abbreviation:  Pediatr Emerg Care     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8507560     Medline TA:  Pediatr Emerg Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  854-6     Citation Subset:  IM    
Affiliation:
From the *Department of Pediatrics and Communicable Diseases, and †Children's Emergency Services, Department of Emergency Medicine, University of Michigan, Ann Arbor, MI.
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