Document Detail


Toxic impact of two organophosphate insecticides on biochemical parameters of a food fish and assessment of recovery response.
MedLine Citation:
PMID:  21983276     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Sublethal effects of chlorpyrifos (CPF) and monocrotophos (MCP) on fish biochemical constituents were investigated along with the assessment of recovery response after cessation of intoxication. The fish, Clarias batrachus were exposed to 1.656 mg(-l) and 2.114 mg(-l) of CPF and MCP for 28 days. After 28 days, they were released in freshwater and allowed to recover for 21 days. The CPF exposure resulted in the decrease of carbohydrate and glycogen content, whereas MCP intoxication caused mixed response. Pyruvate and lactate contents were altered under the stress of CPF and MCP. Recovery of these alterations was observed after the cessation of toxicity. Exposure of C. batrachus to CPF and MCP resulted in decreased activity of lactate dehydrogenase in the kidney, liver and muscle but its activity increased in the gills. The CPF caused inhibition of succinate dehydrogenase enzyme in all tissues. Induction in the activity of malate dehydrogenase was caused by both insecticides. Glycogen phosphorylase a was induced in all tissues, whereas glycogen phosphorylase ab showed both induction and inhibition. Of the two insecticides, CPF was more toxic and the recovery response was less. These results are important in the assessment of the risk caused by organophosphate insecticides on nontarget organisms, especially the food fish.
Authors:
Madhusudan Reddy Narra; Ghousia Begum; Kodimyala Rajender; J Venkateswara Rao
Related Documents :
20511516 - To eat or not to eat: the effect of aicar on food intake regulation in yellow-bellied m...
1248916 - Analgesic abuse and personality characteristics.
3800366 - Vomiting reduction by slower food intake.
172316 - The role of acth and adrenal glucocorticoids in the salt appetite of wild rabbits (oryc...
23126326 - Effects of adding food by-products mainly including noodle waste to total mixed ration ...
19791596 - Differential use of identical food resources by reticulitermes flavipes (isoptera: rhin...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-7
Journal Detail:
Title:  Toxicology and industrial health     Volume:  -     ISSN:  1477-0393     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8602702     Medline TA:  Toxicol Ind Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Zoology, College of Science, Osmania University, Hyderabad, Andhra Pradesh, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Acute toxicity bioassay of mercury and silver on Capoeta fusca (black fish).
Next Document:  Psychosis and Dandy-Walker complex: report of four cases.