Document Detail

Toxic and genetic effects of fuel oil photoproducts and three hydroperoxides in Saccharomyces cerevisiae.
MedLine Citation:
PMID:  366161     Owner:  NLM     Status:  MEDLINE    
Phototransformation of no. 2 fuel oil by UV irradiation at wavelengths designed to simulate sunlight resulted in the formation of products toxic to the yeast Saccharomyces cerevisiae. Increasing the time of irradiation of the fuel oil samples increased the toxicity. Fuel oil that had been irradiated for 12 or 24 h was convertagenic to the yeast strain D4. The toxicity and genetic activity of these samples could be removed by treatment with thiacyclohexane. It is thought that hydroperoxides are the primary photoproducts responsible for these biological effects. Of three hydroperoxides tested, tert-butyl was convertagenic and cumene and tetralin were not. However, all three hydroperoxides were toxic to yeast.
D F Callen; R A Larson
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of toxicology and environmental health     Volume:  4     ISSN:  0098-4108     ISO Abbreviation:  J Toxicol Environ Health     Publication Date:    1978 Sep-Nov
Date Detail:
Created Date:  1979-03-13     Completed Date:  1979-03-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7513622     Medline TA:  J Toxicol Environ Health     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  913-7     Citation Subset:  IM    
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MeSH Terms
Fuel Oils / analysis,  radiation effects,  toxicity*
Peroxides / toxicity*
Petroleum / toxicity*
Saccharomyces cerevisiae / drug effects*,  genetics
Ultraviolet Rays
Reg. No./Substance:
0/Fuel Oils; 0/Peroxides; 0/Petroleum

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