Document Detail

Toxic gas inhalation.
MedLine Citation:
PMID:  15786599     Owner:  NLM     Status:  MEDLINE    
Severe toxic fume inhalations, usually accidental due to human error or equipment failure, can result in immediate death from asphyxia or cause mild to severe respiratory distress from acute upper airways inflammation, delayed pulmonary edema, respiratory muscle dysfunction, or a combination of illnesses. Most patients are expected to survive and recover with little or no residual dysfunction regardless of the severity of the initial event. However, in some cases disabling long-term sequelae, eg, bronchiectasis, chronic airflow obstruction, bronchial hyperreactivity, asthma-like disease (reactive airways dysfunction syndrome), bronchiolitis obliterans, or residual psychophysiologic dyspnea, can occur. Therapy of the respiratory effects of irritant gases should follow the general principles used for the treatment of upper and lower airway obstruction, noncardiogenic pulmonary edema, and hemorrhagic pneumonitis while spontaneous healing and recovery occurs, because no specific therapy is available for direct chemical pulmonary injury. Corticosteroids are frequently used and recommended, but their efficacy in altering the course and outcome of respiratory injury has not yet been properly documented.
G A do Pico
Related Documents :
1881589 - Axonal regeneration from central respiratory neurons of the adult rat into peripheral n...
17350689 - Pathophysiology of respiratory failure following acute dichlorvos poisoning in a rodent...
11503159 - Combination of renal agenesis with respiratory and alimentary tract atresia results in ...
15786599 - Toxic gas inhalation.
25252499 - Calciphylaxis leading to penile necrosis.
16880369 - Respiratory-related evoked potential elicited in tracheostomised lung transplant patients.
7614379 - Recovery period from ureteral obstructions of different duration and severity in the ra...
15017529 - Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in chronic r...
21168599 - Sequential transplant of paired kidneys following donation after cardiac death: impact ...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in pulmonary medicine     Volume:  1     ISSN:  1070-5287     ISO Abbreviation:  Curr Opin Pulm Med     Publication Date:  1995 Mar 
Date Detail:
Created Date:  2005-03-24     Completed Date:  2005-04-19     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9503765     Medline TA:  Curr Opin Pulm Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  102-8     Citation Subset:  IM    
Pulmonary and Critical Care Medicine, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Environmental Exposure*
Glucocorticoids / therapeutic use
Intubation, Intratracheal
Occupational Exposure*
Respiratory Insufficiency / chemically induced
Respiratory Tract Diseases / chemically induced*
Reg. No./Substance:
0/Gases; 0/Glucocorticoids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Burns and smoke inhalation.
Next Document:  Bronchiolitis with airflow obstruction.