Document Detail


Toxic gas inhalation.
MedLine Citation:
PMID:  15786599     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Severe toxic fume inhalations, usually accidental due to human error or equipment failure, can result in immediate death from asphyxia or cause mild to severe respiratory distress from acute upper airways inflammation, delayed pulmonary edema, respiratory muscle dysfunction, or a combination of illnesses. Most patients are expected to survive and recover with little or no residual dysfunction regardless of the severity of the initial event. However, in some cases disabling long-term sequelae, eg, bronchiectasis, chronic airflow obstruction, bronchial hyperreactivity, asthma-like disease (reactive airways dysfunction syndrome), bronchiolitis obliterans, or residual psychophysiologic dyspnea, can occur. Therapy of the respiratory effects of irritant gases should follow the general principles used for the treatment of upper and lower airway obstruction, noncardiogenic pulmonary edema, and hemorrhagic pneumonitis while spontaneous healing and recovery occurs, because no specific therapy is available for direct chemical pulmonary injury. Corticosteroids are frequently used and recommended, but their efficacy in altering the course and outcome of respiratory injury has not yet been properly documented.
Authors:
G A do Pico
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in pulmonary medicine     Volume:  1     ISSN:  1070-5287     ISO Abbreviation:  Curr Opin Pulm Med     Publication Date:  1995 Mar 
Date Detail:
Created Date:  2005-03-24     Completed Date:  2005-04-19     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9503765     Medline TA:  Curr Opin Pulm Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  102-8     Citation Subset:  IM    
Affiliation:
Pulmonary and Critical Care Medicine, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA.
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MeSH Terms
Descriptor/Qualifier:
Environmental Exposure*
Gases
Glucocorticoids / therapeutic use
Humans
Intubation, Intratracheal
Occupational Exposure*
Prognosis
Respiratory Insufficiency / chemically induced
Respiratory Tract Diseases / chemically induced*
Chemical
Reg. No./Substance:
0/Gases; 0/Glucocorticoids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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