Document Detail


Toxic epidermal necrolysis treated with cyclosporin and granulocyte colony stimulating factor.
MedLine Citation:
PMID:  9425696     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A patient developed toxic epidermal necrolysis while on carbamazepine, 80% of her skin surface being involved. She also developed a pancytopenia with a neutropenia of 0.77 x 10(9)/l (normal range 2-7.5 x 10(9)/l), but was treated with cyclosporin and granulocyte colony stimulating factor and made a full recovery.
Authors:
P Jarrett; M Rademaker; J Havill; H Pullon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and experimental dermatology     Volume:  22     ISSN:  0307-6938     ISO Abbreviation:  Clin. Exp. Dermatol.     Publication Date:  1997 May 
Date Detail:
Created Date:  1998-01-27     Completed Date:  1998-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7606847     Medline TA:  Clin Exp Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  146-7     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Health Waikato, New Zealand.
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MeSH Terms
Descriptor/Qualifier:
Adult
Analgesics, Non-Narcotic / adverse effects
Carbamazepine / adverse effects
Cyclosporine / therapeutic use*
Epidermal Necrolysis, Toxic / therapy*
Female
Filgrastim / therapeutic use*
Humans
Immunosuppressive Agents / therapeutic use*
Neutropenia / chemically induced,  therapy
Recombinant Proteins / therapeutic use
Chemical
Reg. No./Substance:
0/Analgesics, Non-Narcotic; 0/Immunosuppressive Agents; 0/Recombinant Proteins; 121181-53-1/Filgrastim; 298-46-4/Carbamazepine; 59865-13-3/Cyclosporine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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