| Toxic epidermal necrolysis in a premature infant of 27 weeks' gestational age. | |
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MedLine Citation:
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PMID: 15656816 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Toxic epidermal necrolysis (TEN) is very rare in the newborn period. So far, three cases of TEN in newborns have been reported worldwide. We report a premature infant of 27 weeks' gestational age with TEN at 4 weeks of age. Sepsis treated by an antibiotic combination regimen preceding the TEN was a common feature of all four cases. In our patient, coagulase-negative staphylococci could be identified by blood culture, whereas the previously reported patients suffered from Klebsiella pneumoniae sepsis or Escherichia coli sepsis. Possibly, the uniform association with septic infection in the cases of TEN in the neonatal period might hint at a causal association, thus differentiating it from TEN in older children or adults. |
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Authors:
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K Lohmeier; M Megahed; K W Schulte; H Stannigel; E Mayatepek; H Schroten |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The British journal of dermatology Volume: 152 ISSN: 0007-0963 ISO Abbreviation: Br. J. Dermatol. Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-01-19 Completed Date: 2005-04-14 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0004041 Medline TA: Br J Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 150-1 Citation Subset: IM |
Affiliation:
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Department of General Paediatrics, Heinrich-Heine-University, Moorenstrasse 5, 40225 Duesseldorf, Germany. lohmeier@uni-duesseldorf.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents Diseases in Twins / etiology* Drug Therapy, Combination / adverse effects Epidermal Necrolysis, Toxic / etiology*, pathology Fatal Outcome Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases / etiology*, pathology Male Sepsis / complications Staphylococcal Infections / complications |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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