Document Detail

Toxic epidermal necrolysis caused by over the counter eyedrops.
MedLine Citation:
PMID:  22897159     Owner:  NLM     Status:  Publisher    
We present a case of a 15-year-old boy who developed toxic epidermal necrolysis (TEN) from sulfacetamide eyedrops. He presented with conjunctival injection and an erythematous rash that rapidly progressed to epidermal necrosis of over 30% of his body. A skin biopsy revealed an acute lichenoid reaction pattern consistent with TEN. After 22 days in hospital, he was left with significant scarring to his eyes, mouth and anogenital areas. An extensive search for an infective aetiology was negative. Previously exposed to bactrim tablets, he used Bleph-10 eyedrops 3 days before admission to hospital. The patient had a strong family history of sulphur allergy. The onset of TEN after topical administration of medication has been reported rarely in the literature. This case highlights the need for a thorough medication history that includes topical preparations.
Lisa Byrom; Tania Zappala; Jim Muir
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-17
Journal Detail:
Title:  The Australasian journal of dermatology     Volume:  -     ISSN:  1440-0960     ISO Abbreviation:  Australas. J. Dermatol.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0135232     Medline TA:  Australas J Dermatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors Australasian Journal of Dermatology © 2012 The Australasian College of Dermatologists.
Mackay Base Hospital, Mackay.
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