| Toxic epidermal necrolysis associated with flea dips. | |
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MedLine Citation:
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PMID: 1621364 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 5-y-old intact female Himalayan cat was dipped with an organophosphate-based compound for flea infestation. The animal subsequently died of organophosphate intoxication. Skin lesions present at necropsy were diagnosed microscopically as toxic epidermal necrolysis. A 5-y-old spayed female Corgi dog was dipped with a d-limonene-based compound for flea infestation. The dog subsequently developed a bullous skin disorder which rapidly progressed to severe coalescing necrotizing dermatitis with large areas of skin sloughing. The dog was treated for a tentative diagnosis of toxic epidermal necrolysis with a short course of corticosteroids and extensive supportive care and recovered completely. Flea dip preparations have the potential to induce severe immune-mediated dermatopathies such as toxic epidermal necrolysis. |
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Authors:
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A A Frank; J L Ross; B K Sawvell |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Veterinary and human toxicology Volume: 34 ISSN: 0145-6296 ISO Abbreviation: Vet Hum Toxicol Publication Date: 1992 Feb |
Date Detail:
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Created Date: 1992-08-06 Completed Date: 1992-08-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7704194 Medline TA: Vet Hum Toxicol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 57-61 Citation Subset: IM |
Affiliation:
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College of Veterinary Medicine, Oregon State University, Corvallis 97331-4802. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cat Diseases / chemically induced*, pathology Cats Cyclohexenes Dog Diseases / chemically induced*, pathology Dogs Ectoparasitic Infestations / therapy, veterinary Epidermal Necrolysis, Toxic / etiology, veterinary* Female Fleas Insecticides / adverse effects* Phosmet / adverse effects* Terpenes / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Cyclohexenes; 0/Insecticides; 0/Terpenes; 138-86-3/limonene; 732-11-6/Phosmet |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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