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Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin.
MedLine Citation:
PMID:  19901485     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Ciprofloxacin is one of the most commonly used antibacterial agents with relatively few side effects. Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0.6%. Recently we came across two rare adverse effects of ciprofloxacin, viz. toxic epidermal necrolysis and agranulocytosis. To our knowledge, a total of seven cases have been reported in the literature documenting an association between oral ciprofloxacin administration and toxic epidermal necrolysis. One case of granulocytopenia, four of pancytopenia and fifteen of leucopenia worldwide have been reported. With the use of ciprofloxacin becoming more and more widespread, these two rare but fatal complications of ciprofloxacin should be borne in mind.
Authors:
Gatha M Upadya; K Ruxana
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of medical sciences     Volume:  63     ISSN:  1998-3654     ISO Abbreviation:  Indian J Med Sci     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-11-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373023     Medline TA:  Indian J Med Sci     Country:  India    
Other Details:
Languages:  eng     Pagination:  461-3     Citation Subset:  IM    
Affiliation:
Department of Skin and STD, K. M. C. Hospital, Attavar, Mangalore, India. gathaupadya@hotmail.com
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