Document Detail

Toxic effects of acute exposure to particular xylene isomers in animals.
MedLine Citation:
PMID:  2130876     Owner:  NLM     Status:  MEDLINE    
The effect of exposure to particular xylene isomers at a concentration of 3000 ppm on rotarod performance in rats and the respiratory rate in mice was investigated. Rotarod performance was tested in rats immediately after termination of a 6-hour exposure, and the respiratory rate in mice was recorded during a short 6 minute exposure to individual xylene isomers. In both rats and mice the toxic effects of exposure to ortho- and meta-xylene were more pronounced than that of para-xylene.
Z Korsak; J A Sokal; T Wasiela; R Swiercz
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Polish journal of occupational medicine     Volume:  3     ISSN:  0860-6536     ISO Abbreviation:  Pol J Occup Med     Publication Date:  1990  
Date Detail:
Created Date:  1991-12-09     Completed Date:  1991-12-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9012925     Medline TA:  Pol J Occup Med     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  221-6     Citation Subset:  IM    
Department of Toxicity Evaluation, Nofer Institute of Occupational Medicine, Lodz, Poland.
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MeSH Terms
Acute Disease
Mice, Inbred BALB C
Neuromuscular Junction / drug effects
Rats, Inbred Strains
Respiration / drug effects
Xylenes / toxicity*
Reg. No./Substance:

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