Document Detail

Towards sutureless non-occlusive cerebral revascularization.
MedLine Citation:
PMID:  21623324     Owner:  NLM     Status:  In-Data-Review    
Sutureless vascular anastomoses have been the subject of extensive research for decades. In neurosurgery the need for a safe and fast technique is high, because temporary occlusion of cerebral arteries may rapidly lead to brain ischemia. Conventional sutured anastomoses have always been the golden standard. Limited working space and difficult suturing techniques were reasons to find alternatives. Many artificial devices to create anastomoses have been engineered over the years like tissue sealants, clips and automated suturing sets with variable success. For all previous options, temporary occlusion of the recipient artery was necessary. The Excimer Laser Assisted Non-Occlusive Anastomosis (ELANA) technique™ facilitates the construction of an end-to-side anastomosis without temporary occlusion of the recipient artery using a platinum ring and a laser. However, the technical challenge of intracranial micro-sutures remained. Experiments using less sutures eventually resulted in a sutureless ELANA (SELANA) anastomosis. After in vitro and in vivo experiments, the SELANA slide was considered feasible for intracranial use although some concrete improvements, like the inclusion of a clip at the back of the device, were needed. Therefore, the development of an ideal sutureless anastomosis is still ongoing. This process is an evolution rather than a revolution.
B De Boer; T P Van Doormaal; A Van Der Zwan; C A Tulleken; L Regli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgical sciences     Volume:  55     ISSN:  0390-5616     ISO Abbreviation:  J Neurosurg Sci     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0432557     Medline TA:  J Neurosurg Sci     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  117-25     Citation Subset:  IM    
Department of Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center of Utrech, Utrecht, The Netherlands -
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