| Towards risk stratification in systemic atherosclerosis: value of myocardial function and viability imaging as an adjunct to MR angiography. | |
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MedLine Citation:
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PMID: 19760234 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To longitudinally assess the value of cardiac functional and viability imaging as a supplement to MR angiography in patients with atherosclerotic disease. METHODS: Cardiac MRI was performed in 195 consecutive patients with symptomatic peripheral arterial disease. Of these, 186 patients were followed for 22 +/- 5 months for the presence of cardiac events (cardiac death, acute coronary syndrome and hospitalisation as a result of congestive heart failure). RESULTS: Myocardial viability imaging showed a high prevalence of known (n = 31) and occult myocardial infarctions (MI) (n = 26). Cardiac events occurred more often in patients with reduced ventricular function (ejection fraction (EF) less than 40%, cardiac event in 4/8 patients; EF 40-55%, cardiac event in 10/40 patients; EF greater than 55%, cardiac event in 15/138 patients) as well as in patients with occult MI (8/25 patients) and known MI (11/30 patients). In patients with normal function, the detection of a previous MI was of high relevance to prognosis. CONCLUSIONS: Both reduced EF and the presence of MI influence patients' prognoses. Performing cardiac MRI in this patient population may influence further patient management including intensified risk factor intervention. |
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Authors:
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Achim Seeger; Michael Fenchel; Ulrich Kramer; Christiane Bretschneider; Florian Grimm; Bernhard Klumpp; Albertus Scheule; Bernd Balletshofer; Claus D Claussen; Stephan Miller |
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Publication Detail:
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Type: Journal Article Date: 2009-09-16 |
Journal Detail:
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Title: European radiology Volume: 20 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-10 Completed Date: 2010-06-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 838-45 Citation Subset: IM |
Affiliation:
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Department of Diagnostic and Interventional Radiology, Eberhard Karls University Tuebingen, Tuebingen, Germany. achim.seeger@med.uni-tuebingen.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Atherosclerosis / diagnosis*, epidemiology* Comorbidity Female Germany / epidemiology Heart Diseases / diagnosis*, epidemiology* Humans Magnetic Resonance Angiography / statistics & numerical data* Male Prevalence Prognosis Reproducibility of Results Risk Assessment / methods Risk Factors Sensitivity and Specificity Tissue Survival |
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