Document Detail

Towards risk stratification in systemic atherosclerosis: value of myocardial function and viability imaging as an adjunct to MR angiography.
MedLine Citation:
PMID:  19760234     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To longitudinally assess the value of cardiac functional and viability imaging as a supplement to MR angiography in patients with atherosclerotic disease. METHODS: Cardiac MRI was performed in 195 consecutive patients with symptomatic peripheral arterial disease. Of these, 186 patients were followed for 22 +/- 5 months for the presence of cardiac events (cardiac death, acute coronary syndrome and hospitalisation as a result of congestive heart failure). RESULTS: Myocardial viability imaging showed a high prevalence of known (n = 31) and occult myocardial infarctions (MI) (n = 26). Cardiac events occurred more often in patients with reduced ventricular function (ejection fraction (EF) less than 40%, cardiac event in 4/8 patients; EF 40-55%, cardiac event in 10/40 patients; EF greater than 55%, cardiac event in 15/138 patients) as well as in patients with occult MI (8/25 patients) and known MI (11/30 patients). In patients with normal function, the detection of a previous MI was of high relevance to prognosis. CONCLUSIONS: Both reduced EF and the presence of MI influence patients' prognoses. Performing cardiac MRI in this patient population may influence further patient management including intensified risk factor intervention.
Achim Seeger; Michael Fenchel; Ulrich Kramer; Christiane Bretschneider; Florian Grimm; Bernhard Klumpp; Albertus Scheule; Bernd Balletshofer; Claus D Claussen; Stephan Miller
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Publication Detail:
Type:  Journal Article     Date:  2009-09-16
Journal Detail:
Title:  European radiology     Volume:  20     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-06-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  838-45     Citation Subset:  IM    
Department of Diagnostic and Interventional Radiology, Eberhard Karls University Tuebingen, Tuebingen, Germany.
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MeSH Terms
Atherosclerosis / diagnosis*,  epidemiology*
Germany / epidemiology
Heart Diseases / diagnosis*,  epidemiology*
Magnetic Resonance Angiography / statistics & numerical data*
Reproducibility of Results
Risk Assessment / methods
Risk Factors
Sensitivity and Specificity
Tissue Survival

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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