Document Detail

Towards the rational design of cereal starches.
MedLine Citation:
PMID:  15753002     Owner:  NLM     Status:  MEDLINE    
A major challenge in cereal biotechnology is to achieve the rational design of renewable polymers to meet specific requirements for improving human health, nutrition, and food quality, to increase the energy supply, and to provide safer and more profitable industrial inputs. The field of starch synthesis research has advanced at a rapid pace over the past decade, and many core observations about the pathway are well established over a range of species. Owing to the complexity of the starch-synthesis process, in which suites of enzymes act at the interface between soluble and insoluble phases, the rational design of starch granules with specific functionality is still in its infancy. Our fundamental biochemical knowledge of starch biosynthesis has recently advanced, and this new information could be exploited to create novel variability in carbohydrate polymers in cereal grains. We propose two strategies for moving more rapidly towards truly rational design of starch. First, the focusing of fundamental research on processes that are involved in the regulation of starch synthesis and granule assembly. Second, the development of iterative strategies, exploiting new molecular genetics tools, to screen for desired properties in high-throughput systems.
Matthew K Morell; Alan M Myers
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in plant biology     Volume:  8     ISSN:  1369-5266     ISO Abbreviation:  Curr. Opin. Plant Biol.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-03-08     Completed Date:  2005-05-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100883395     Medline TA:  Curr Opin Plant Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  204-10     Citation Subset:  IM    
CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia.
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MeSH Terms
Biotechnology / methods
Cereals / genetics,  metabolism*,  standards
Starch / biosynthesis*,  chemistry,  genetics,  standards
Reg. No./Substance:

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