| Towards multifocal ultrasonic neural stimulation II: design considerations for an acoustic retinal prosthesis. | |
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MedLine Citation:
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PMID: 22326949 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Ultrasound waves, widely used as a non-invasive diagnostic modality, were recently shown to stimulate neuronal activity. Functionally meaningful stimulation, as is required in order to form a unified percept, requires the dynamic generation of simultaneous stimulation patterns. In this paper, we examine the general feasibility and properties of an acoustic retinal prosthesis, a new vision restoration strategy that will combine ultrasonic neuro-stimulation and ultrasonic field sculpting technology towards non-invasive artificial stimulation of surviving neurons in a degenerating retina. We explain the conceptual framework for such a device, study its feasibility in an in vivo ultrasonic retinal stimulation study and discuss the associated design considerations and tradeoffs. Finally, we simulate and experimentally validate a new holographic method-the angular spectrum-GSW-for efficient generation of uniform and accurate continuous ultrasound patterns. This method provides a powerful, flexible solution to the problem of projecting complex acoustic images onto structures like the retina. |
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Authors:
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Omer Naor; Yoni Hertzberg; Esther Zemel; Eitan Kimmel; Shy Shoham |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-13 |
Journal Detail:
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Title: Journal of neural engineering Volume: 9 ISSN: 1741-2552 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101217933 Medline TA: J Neural Eng Country: - |
Other Details:
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Languages: ENG Pagination: 026006 Citation Subset: - |
Affiliation:
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Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa, Israel. The Interdisciplinary Centre for Neural Computation, Hebrew University, Jerusalem, Israel. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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