| Towards hemostatic resuscitation: the changing understanding of acute traumatic biology, massive bleeding, and damage-control resuscitation. | |
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MedLine Citation:
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PMID: 22850152 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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During the past decade there has been a profound change in the understanding of postinjury coagulation. Concurrently, new data suggest that a resuscitative strategy to minimize large volumes of crystalloid while recreating whole is associated with reduced morbidity and mortality. This article outlines the history of resuscitation and transfusion practices in trauma, the changing understanding of coagulation and inflammation, and clinical data driving changes in resuscitative conduct. Finally, the current state of the science suggests future basic science and clinical investigation that will drive changes in transfusion and resuscitation in severely injured military personnel and civilian patients. |
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Authors:
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Mitchell Jay Cohen |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Surgical clinics of North America Volume: 92 ISSN: 1558-3171 ISO Abbreviation: Surg. Clin. North Am. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-08-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0074243 Medline TA: Surg Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 877-91 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2012. Published by Elsevier Inc. |
Affiliation:
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Department of Surgery, San Francisco General Hospital and the University of California, San Francisco, 1001 Potrero Avenue, Ward 3A, San Francisco, CA 94110, USA. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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