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Towards a four-dimensional view of neutrophils.
MedLine Citation:
PMID:  22262436     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Neutrophils are constitutively produced throughout adult life and are essential for host responses to many types of pathogen. Neutropenia has long been associated with poor prognosis in the clinic, yet we have an incomplete understanding of their life cycle, not only during homeostasis but also during infection and chronic inflammation. Here, we review recent advances that provide insight into the genetic and biochemical regulators of neutrophil production, function, and survival.
Authors:
Ben A Croker; Andrew W Roberts; Nicos A Nicola
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  844     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2012  
Date Detail:
Created Date:  2012-01-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  87-99     Citation Subset:  IM    
Affiliation:
The Walter and Eliza Hall Institute, 1G Royal Parade, Parkville, Australia, croker@wehi.edu.au.
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