Document Detail


Towards dynamic control of magnetic fields to focus magnetic carriers to targets deep inside the body.
MedLine Citation:
PMID:  20165553     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Magnetic drug delivery has the potential to target therapy to specific regions in the body, improving efficacy and reducing side effects for treatment of cancer, stroke, infection, and other diseases. Using stationary external magnets, which attract the magnetic drug carriers, this treatment is limited to shallow targets (<5 cm below skin depth using the strongest possible, still safe, practical magnetic fields). We consider dynamic magnetic actuation and present initial results that show it is possible to vary magnets one against the other to focus carriers between them on average. The many remaining tasks for deep targeting in-vivo are then briefly noted.
Authors:
Benjamin Shapiro
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of magnetism and magnetic materials     Volume:  321     ISSN:  0304-8853     ISO Abbreviation:  -     Publication Date:  2009 May 
Date Detail:
Created Date:  2010-7-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101314425     Medline TA:  J Magn Magn Mater     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1594     Citation Subset:  -    
Affiliation:
Bio-Engineering/Aerospace Engineering, 3178 Martin Hall, University of Maryland at College Park, College Park, MD 20742, USA.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R21 EB009265-01A2//NIBIB NIH HHS

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