Document Detail

Towards an artificial cell.
MedLine Citation:
PMID:  22841716     Owner:  NLM     Status:  MEDLINE    
We are on the verge of producing "synthetic cells," or protocells, in which some, many or all of the tasks of a real biological cell are harnessed into a synthetic platform. Such advances are made possible through genetic engineering, microfabrication technologies, and the development of cellular membranes from new surfactants that extend beyond phospholipids in stability and chemical control, and can be used to introduce designer functionality into membranes and cells. We review some of the recent advances in the development of synthetic cells and suggest future exciting directions.
Daniel A Hammer; Neha P Kamat
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review     Date:  2012-07-25
Journal Detail:
Title:  FEBS letters     Volume:  586     ISSN:  1873-3468     ISO Abbreviation:  FEBS Lett.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-08-13     Completed Date:  2012-10-23     Revised Date:  2012-12-19    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  2882-90     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
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MeSH Terms
Artificial Cells*
Genetic Engineering
Phospholipids / metabolism
Surface-Active Agents / metabolism
Reg. No./Substance:
0/Phospholipids; 0/Surface-Active Agents
Erratum In:
FEBS Lett. 2012 Oct 19;586(20):3766

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