| Toward a neurodynamical understanding of ictogenesis. | |
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MedLine Citation:
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PMID: 14641559 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although considerable information on cellular and network mechanisms of epilepsy exists, it is still not understood why, how, and when the transition from interictal to ictal state takes place. The authors review their work on nonlinear EEG analysis and provide consistent evidences that dynamical changes in the neural activity allows the characterization of a preictal state several minutes before seizure onset. This new neurodynamical approach of ictogenesis opens new perspectives for studying the basic mechanisms in epilepsy as well as for possible therapeutic interventions. |
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Authors:
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Michel Le Van Quyen; Vincent Navarro; Jacques Martinerie; Michel Baulac; Francisco J Varela |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Epilepsia Volume: 44 Suppl 12 ISSN: 0013-9580 ISO Abbreviation: Epilepsia Publication Date: 2003 |
Date Detail:
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Created Date: 2003-12-03 Completed Date: 2004-02-12 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
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Languages: eng Pagination: 30-43 Citation Subset: IM |
Affiliation:
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LENA (Laboratoire de Neurosciences Cognitives et Imagerie Cérébrale), CNRS UPR 640, Hôpital de la Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, 75651 Paris cedex 13, France. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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physiopathology* Diagnosis, Differential Electroencephalography Epilepsy / diagnosis*, physiopathology* Humans Neural Inhibition / physiology Neurosciences / methods Scalp Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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