| Toward a criterion for suspect thiouracil administration in animal husbandry. | |
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MedLine Citation:
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PMID: 21547795 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Thyreostats are growth-promoters banned in Europe since 1981. The identification of thiouracil (TU) in animal biological matrices can, however, no longer be systematically interpreted as a consequence of illegal administration. Indeed, some experimental results have indicated a causal link between cruciferous-based diet and the presence of TU in urine of bovines. The present study aims at investigating, on a large scale (n > 1300), the natural occurrence of thiouracil in urine samples collected from different animal species. TU was identified in main breeding animal species: bovine, porcine and ovine. The natural distribution of TU allowed proposing threshold values to differentiate compliant from suspect urine samples. Suggested values are 5.7 and 9.1 µg l(-1) in male adult bovines (6-24 months), 3.1 and 8.1 µg l(-1) in female adult bovines (6-24 months), 7.3 and 17.7 µg l(-1) in calves (<6 months), 3.9 and 8.8 µg l(-1) in female bovines (>24 months), and 2.9 and 4.1 µg l(-1) in porcines at a 95 and 99% confidence level, respectively. |
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Authors:
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Bruno Le Bizec; Emmanuelle Bichon; Yoann Deceuninck; Stephanie Prevost; Fabrice Monteau; Jean-Philippe Antignac; Gaud Dervilly-Pinel |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-01 |
Journal Detail:
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Title: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment Volume: - ISSN: 1944-0057 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-5-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101485040 Medline TA: Food Addit Contam Part A Chem Anal Control Expo Risk Assess Country: - |
Other Details:
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Languages: ENG Pagination: 1-8 Citation Subset: - |
Affiliation:
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ONIRIS, Ecole Nationale Veterinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique, Laboratoire d'Etude des Residus et Contaminants dans les Aliments (LABERCA), Atlanpole - La Chantrerie, BP 40706, Nantes F-44307, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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