Document Detail


Tourette's syndrome is not associated with interleukin-10 receptor 1 variants on chromosome 11q23.3.
MedLine Citation:
PMID:  17961716     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Interleukin-10 receptor 1 (IL-10R1) single nucleotide polymorphisms, located on chromosome 11q23 - a strong candidate for linkage with Tourette's syndrome (TS) - have been investigated for association with TS. DNA of 77 patients with a DSM-IV (Diagnostic and Statistical Manual IV) diagnosis of TS and 250 healthy controls was genotyped. IL-10R1 was not associated with TS.
Authors:
Jochen Kindler; Alexandra Schosser; Mara Stamenkovic; Monika Schloegelhofer; Friedrich Leisch; Kurt Hornik; Harald Aschauer; Christoph Gasche
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-10-24
Journal Detail:
Title:  Psychiatry research     Volume:  157     ISSN:  0165-1781     ISO Abbreviation:  Psychiatry Res     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-06     Completed Date:  2008-03-25     Revised Date:  2008-04-17    
Medline Journal Info:
Nlm Unique ID:  7911385     Medline TA:  Psychiatry Res     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  235-9     Citation Subset:  IM    
Affiliation:
Department of Biological Psychiatry, University Hospital of Psychiatry and Psychotherapy, Medical University of Vienna, Austria. jochen.kindler@gef.be.ch
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MeSH Terms
Descriptor/Qualifier:
Adult
Alleles
Autoantibodies / immunology
Chromosomes, Human, Pair 11 / genetics*
Female
Genotype
Humans
Interleukin-10 Receptor alpha Subunit / genetics*,  immunology
Male
Polymerase Chain Reaction
Tourette Syndrome / genetics*,  immunology
Chemical
Reg. No./Substance:
0/Autoantibodies; 0/Interleukin-10 Receptor alpha Subunit

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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