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Totally implantable central venous access ports in patients with cystic fibrosis: a multicenter prospective cohort study.
MedLine Citation:
PMID:  22266592     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Purpose: The aim of this study was to assess the incidence of late onset complications of totally implantable venous access devices (TIVAD) in patients with cystic fibrosis (CF) and to investigate possible associations between the rate of complications and different policies of TIVAD management. Methods: A multicenter prospective cohort study was performed in 11 Italian CF Centers. Patients with CF and a TIVAD were recruited and followed-up. Results: The study commenced on May 2008 and ended on September 2010. Eighty subjects were studied (77.5% women - mean age 27.2 years). Eighteen late complications of ports were observed (22.5%; incidence 0.96 per 1000 days of observation): three lumen occlusions, seven catheter-related infections , three port-related venous thrombosis, in addition to five other complications. A statistically significant association was found between the onset of catheter-related infection and the presence of CF-related diabetes (CFRD) (P=.0064) Conclusions: Our data suggest that TIVADs represent a safe and effective device for the intermittent IV administration of drugs in people with CF. However, people with CFRD have a higher risk of developing TIVAD-related catheter-related infection. The authors wish to thank Mauro Pittiruti (National Coordinator of GAVeCeLT, the Italian Group for Long-Term Venous Access Devices, www.gavecelt.info) for his advice in reviewing the manuscript.
Authors:
Alberto Dal Molin; Dino Stefano Di Massimo; Cesare Braggion; Sofia Bisogni; Elena Rizzi; Ciro D'Orazio; Maria Vittoria Di Toppa; Federico Alghisi; Simona Cristadoro; Vincenzo Carnovale; Gabriella Festa; Serena Rampini; Carla Colombo; Anna Oneta; Maria Lucia Furnari; Maria Antonietta Calamia; Maria Luisa Zunino; Giuseppe Tuccio; Vincenzo Spadea; Barbara Messore; Bianca Grosso; Filippo Festini
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-10
Journal Detail:
Title:  The journal of vascular access     Volume:  -     ISSN:  1724-6032     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100940729     Medline TA:  J Vasc Access     Country:  -    
Other Details:
Languages:  ENG     Pagination:  0     Citation Subset:  -    
Affiliation:
Nursing School, Biella Hospital, University of Piemonte Orientale - Italy.
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