Document Detail

Total skin electron beam (TSEB) therapy in pediatric patients: A review of the literature.
MedLine Citation:
PMID:  24936329     Owner:  NLM     Status:  PubMed-not-MEDLINE    
AIM: A literature review was undertaken to identify current TSEB therapy in pediatric patients.
BACKGROUND: Total skin electron beam (TSEB) therapy is a method of irradiation with low energy electron beam dedicated to patients who have superficial skin lesions all over their body. Such skin malignancies are sparse among adults and even more uncommon with pediatric population.
MATERIALS AND METHODS: In this study, all reported case reports were summed up with a special emphasis on techniques used, doses prescribed and special shielding of critical organs. Moreover, potential problems that were encountered during TSEB irradiation of very young patients were depicted.
RESULTS: The literature has described only seven case reports of children undergoing TSEB therapy. Most of them were infants; however, two adolescents were also treated. For all infants, general anesthesia was provided to allow safe and accurate TSEB irradiation. The prescribed dose varied from 16 Gy to 28 Gy depending on the irradiation schedule and patient condition. Usually, boost fields were applied to the scalp and perineum. Typical shields for fingernails, toenails and lenses were usually used.
CONCLUSION: This paper revealed that TSEB therapy may be considered as a palliative treatment for pediatric patients with leukemia cutis. However, its role is still unclear and should be further investigated.
Małgorzata Skórska
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Publication Detail:
Type:  Journal Article; Review     Date:  2013-07-19
Journal Detail:
Title:  Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology     Volume:  19     ISSN:  1507-1367     ISO Abbreviation:  Rep Pract Oncol Radiother     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-06-17     Completed Date:  2014-06-24     Revised Date:  2014-06-24    
Medline Journal Info:
Nlm Unique ID:  100885761     Medline TA:  Rep Pract Oncol Radiother     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  109-13     Citation Subset:  -    
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