Document Detail

Total respiratory compliance during anaesthesia in infants and young children.
MedLine Citation:
PMID:  2803884     Owner:  NLM     Status:  MEDLINE    
The multiple occlusion technique was used to study the effects of paralysis on ventilatory mechanics during anaesthesia. Total respiratory compliance (Crs) was measured during spontaneous breathing and following neuromuscular block with controlled ventilation in 23 infants. There was marked variation in response to paralysis: some infants demonstrated no change in Crs between the two states; others had values of Crs which were significantly higher during paralysis with controlled ventilation than during spontaneous breathing. A possible cause of these differences may be the type of controlled ventilation given during paralysis, with tidal volume directly influencing values of Crs obtained. The results of this study suggest that values of Crs obtained during spontaneous breathing and paralysis should not be used interchangeably until further studies have been performed to assess factors influencing Crs during controlled ventilation.
M E Fletcher; J Stocks; S Ridley; N Braude; A P Yates; D J Hatch
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  63     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-12-15     Completed Date:  1989-12-15     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  266-75     Citation Subset:  IM    
Hospital for Sick Children, London.
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MeSH Terms
Anesthesia, General*
Child, Preschool
Lung Compliance*
Neuromuscular Blocking Agents*
Respiration, Artificial*
Respiratory Physiological Phenomena
Tidal Volume
Reg. No./Substance:
0/Neuromuscular Blocking Agents

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