Document Detail

Total parenteral nutrition.
MedLine Citation:
PMID:  815725     Owner:  NLM     Status:  MEDLINE    
Total parenteral nutrition (TPN) is a relatively new innovation in patient care which allows us to replace and maintain essential nutrients in patients in whom oral or tube feedings are contraindicated or inadequate. Insertion of a catheter into a large central vein permits one to concentrate hypertonic dextrose calories in normal daily fluid requirements. In addition, TPN solutions contain synthetic amino acids or protein hydrolysates, macroelements, electrolytes, and vitamins. Indications for TPN include intestinal fistulas, severe short bowel syndrome, unresolving pancreatitis, advanced inflammatory bowel disease, delayed postoperative gastrointestinal function, developmental anomalies of the intestinal tract, protracted diarrhea of infancy, and hypermetabolic states. Complications encountered in patients receiving TPN are catheter-related mechanical problems, infections, and metabolic abnormalities. In select patients, who otherwise would require repeated hospitalizations for malnutrition, encouraging results have been achieved by the use of TPN in the home.
C R Fleming; D B McGill; H N Hoffman; R A Nelson
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Publication Detail:
Type:  Historical Article; Journal Article    
Journal Detail:
Title:  Mayo Clinic proceedings     Volume:  51     ISSN:  0025-6196     ISO Abbreviation:  Mayo Clin. Proc.     Publication Date:  1976 Mar 
Date Detail:
Created Date:  1976-05-25     Completed Date:  1976-05-25     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0405543     Medline TA:  Mayo Clin Proc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  187-99     Citation Subset:  IM; Q    
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MeSH Terms
Amino Acids / administration & dosage
Catheterization / methods
Dietary Carbohydrates / metabolism
Dietary Fats / metabolism
History, 19th Century
History, 20th Century
Home Care Services
Infection / complications*
Metabolic Diseases / complications*
Nutritional Physiological Phenomena*
Nutritional Requirements*
Parenteral Nutrition* / history
Parenteral Nutrition, Total* / history
Quality Control
Time Factors
Vitamins / administration & dosage
Reg. No./Substance:
0/Amino Acids; 0/Dietary Carbohydrates; 0/Dietary Fats; 0/Vitamins

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