Document Detail


Total parenteral nutrition for the treatment of severe hyperemesis gravidarum: maternal nutritional effects and fetal outcome.
MedLine Citation:
PMID:  3132667     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hyperemesis gravidarum is a complication of pregnancy that can lead to severe maternal nutritional deprivation. Total parenteral nutrition has been used in pregnancy complicated by hyperemesis gravidarum. However, little has been done to study the nutritional aspects of hyperemesis or the maternal effects of total parenteral nutrition when given during the first trimester of pregnancy. The purpose of this study was to examine the nutritional state of pregnancy complicated by hyperemesis gravidarum and the effects of total parenteral nutrition on maternal nutrition and fetal outcome when given during the first trimester of pregnancy. Using a standard method of indirect calorimetry, the basal metabolic expenditure and adjusted metabolic expenditure were determined, and appropriate calories were calculated for each patient. The patients were then started on total parenteral nutrition. Follow-up indirect calorimetry studies showed improved nutritional status, with return of anabolic parameters. The results of this study support the conclusion that total parenteral nutrition given during the first trimester is a safe and effective method of nutritional support.
Authors:
M G Levine; D Esser
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  72     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-07-22     Completed Date:  1988-07-22     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  102-7     Citation Subset:  AIM; IM    
Affiliation:
Nebraska Methodist Hospital, Omaha.
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MeSH Terms
Descriptor/Qualifier:
Birth Weight
Calorimetry, Indirect
Energy Metabolism
Female
Humans
Hyperemesis Gravidarum / metabolism,  therapy*
Infant, Newborn
Nutritional Status*
Parenteral Nutrition, Total*
Pregnancy
Pregnancy Outcome / metabolism,  therapy*
Pregnancy Trimester, First

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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