| Total folate and folic acid intake from foods and dietary supplements in the United States: 2003-2006. | |
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MedLine Citation:
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PMID: 19923379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The term total folate intake is used to represent folate that occurs naturally in food as well as folic acid from fortified foods and dietary supplements. Folic acid has been referred to as a double-edged sword because of its beneficial role in the prevention of neural tube defects and yet possible deleterious effects on certain cancers and cognitive function. Previous monitoring efforts did not include folic acid from dietary supplements and are therefore not complete. OBJECTIVE: Our objective was to combine data on dietary folate (as measured by two 24-h recalls) and folic acid from dietary supplements (collected with a 30-d frequency questionnaire) with the use of the bias-corrected best power method to adjust for within-person variability. DESIGN: The National Health and Nutrition Examination Survey (NHANES) is a nationally representative, cross-sectional survey. Linear contrasts were constructed to determine differences in dietary and total folate intake for age and racial-ethnic groups by sex; prevalence of inadequate and excessive intakes is presented. RESULTS: In 2003-2006, 53% of the US population used dietary supplements; 34.5% used dietary supplements that contained folic acid. Total folate intake (in dietary folate equivalents) was higher for men (813 +/- 14) than for women (724 +/- 16) and higher for non-Hispanic whites (827 +/- 19) than for Mexican Americans (615 +/- 11) and non-Hispanic blacks (597 +/- 12); 29% of non-Hispanic black women had inadequate intakes. Total folate and folic acid intakes are highest for those aged > or =50 y, and 5% exceed the Tolerable Upper Intake Level. CONCLUSIONS: Improved total folate intake is warranted in targeted subgroups, which include women of childbearing age and non-Hispanic black women, whereas other population groups are at risk of excessive intake. |
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Authors:
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Regan L Bailey; Kevin W Dodd; Jaime J Gahche; Johanna T Dwyer; Margaret A McDowell; Elizabeth A Yetley; Christopher A Sempos; Vicki L Burt; Kathy L Radimer; Mary Frances Picciano |
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Publication Detail:
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Type: Journal Article Date: 2009-11-18 |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 91 ISSN: 1938-3207 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-21 Completed Date: 2010-01-13 Revised Date: 2011-07-19 |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 231-7 Citation Subset: AIM; IM |
Affiliation:
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Office of Dietary Supplements and the National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-7517, USA. baileyr@mail.nih.gov |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Continental Population Groups Cross-Sectional Studies Diet* Dietary Supplements / analysis* Energy Metabolism Ethnic Groups European Continental Ancestry Group Female Folic Acid / analysis*, metabolism Food Analysis* Food Habits Food, Fortified Health Surveys Hispanic Americans Humans Interviews as Topic Male Mexican Americans Middle Aged Sex Characteristics United States Young Adult |
| Chemical | |
Reg. No./Substance:
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59-30-3/Folic Acid |
| Comments/Corrections | |
Comment In:
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Am J Clin Nutr. 2010 May;91(5):1408-9; author reply 1409
[PMID:
20237139
]
Am J Clin Nutr. 2010 Jan;91(1):3-4 [PMID: 19955398 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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