Document Detail

Total cortisol and L/S-ratio in amniotic fluid in late pregnancies complicated by diabetes mellitus.
MedLine Citation:
PMID:  535879     Owner:  NLM     Status:  MEDLINE    
68 samples of amniotic fluid from 47 women with varying severity of diabetes mellitus and 48 samples from 43 normal women were obtained in the 31st to 40th week of pregnancy before onset of labour. The concentration of total cortisol and the L/S-ratio in amniotic flud were determined and related to gestational age. There was a continous rise of total cortisol with advancing gestational age in the diabetic pregnancies similar to that found in normal pregnancy. Diabetic pregnancies were associated with slightly lower amniotic fluid cortisol levels without significant difference to values found in normal pregnancy. The severity of the disease did not affect the cortisol levels in amniotic fluid. There was no correlation between total cortisol levels and L/S-ratios in amniotic fluid. Determination of total cortisol in amniotic fluid can thus not replace measurements of L/S-ratios to predict fetal lung maturation.
H Pschera; I Björkhem; K Carlström; O Lantto; N O Lunell; B Persson; C Somell; M Stangenberg; J Wager
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme     Volume:  11     ISSN:  0018-5043     ISO Abbreviation:  Horm. Metab. Res.     Publication Date:  1979 Nov 
Date Detail:
Created Date:  1980-05-14     Completed Date:  1980-05-14     Revised Date:  2009-02-19    
Medline Journal Info:
Nlm Unique ID:  0177722     Medline TA:  Horm Metab Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  612-5     Citation Subset:  IM    
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MeSH Terms
Amniotic Fluid / analysis*
Hydrocortisone / analysis*
Phosphatidylcholines / analysis
Pregnancy Trimester, Third
Pregnancy in Diabetics / metabolism*
Sphingomyelins / analysis
Reg. No./Substance:
0/Phosphatidylcholines; 0/Sphingomyelins; 50-23-7/Hydrocortisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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