Document Detail


Total artificial heart: the adaptation and pathophysiological deviations in the recipient.
MedLine Citation:
PMID:  12534708     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the short historical review the principal technical and pathophysiological approaches of the Czech total artificial heart (TAH) research are emphasized. Survival was endangered by arterial and venous hypertension, especially the central venous pressure (CVP) increase, mineralization of driving diaphragms, thromboembolization, and infection. By the appropriate combination of antihypertensive, antimineralization, and anticoagulation treatment and of measures against infection, the survival of the experimental calves was increased (the longest one was 314 days of pumping). Technical and constructional improvement of the blood pumps was another cause of successful experiments. All details are issued in the references.
Authors:
J Vasků; P Dobsák
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Artificial organs     Volume:  27     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2003-01-21     Completed Date:  2003-05-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  14-20     Citation Subset:  IM    
Affiliation:
Vacord Bioengineering Research Company, Brno, Czech Republic.
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological / physiology*
Animals
Cardiovascular System / physiopathology*
Cattle
Disease Models, Animal
Heart Diseases / mortality,  physiopathology*,  surgery*
Heart, Artificial / adverse effects*
Hemodynamics / physiology*
Postoperative Complications*
Prosthesis Design
Survival Rate
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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