| Total and antigen-specific IGE levels in umbilical cord blood. | |
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MedLine Citation:
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PMID: 20156762 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study was conducted to learn whether the perinatal and environmental factors could influence the total and antigen-specific IgE levels in umbilical cord blood. Retrospective data were obtained from 173 mother-infant pairs. Total and specific (for children's food, wheat/grass and house dust mite-HDM) cord blood IgE levels were determined using the immunoassay test. The total cord blood IgE was between 0.0-23.08 IU/ml (mean 0.55 +/-2.07 IU/ml; median 0.16 IU/ml). Total IgE levels were significantly higher in boys compared with girls (OR=2.2; P=0.007), and in newborns with complicated pregnancy (OR=2.7; P=0.003). A greater number of siblings correlated with increases in the total cord blood IgE (P<0.02). We detected specific IgE in 34 newborns (40 positive tests). A long-standing contact with a cat during pregnancy decreased the specific IgE level for wheat/grass (OR=3.2; P<0.07) and for children's food (OR=5.0; P<0.04), and the contact with a dog decreased the specific-IgE for wheat/grass (OR=0.3; P<0.05). Exposure to tobacco smoke correlated with the positive specific IgE toward house dust mite (OR=4.7; P=0.005). |
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Authors:
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A J Sybilski; A Doboszynska; B Samolinski |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of medical research Volume: 14 Suppl 4 ISSN: 0949-2321 ISO Abbreviation: Eur. J. Med. Res. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-02-16 Completed Date: 2010-08-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9517857 Medline TA: Eur J Med Res Country: Germany |
Other Details:
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Languages: eng Pagination: 233-6 Citation Subset: IM |
Affiliation:
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Department of Prevention of Envirnomental Hazards and Allergoloy, Warsaw Medical University, Warsaw, Poland. Adam.sybilski@cskmswia.pl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cats Dogs Female Fetal Blood / immunology* Humans Immunoglobulin E / blood* Infant, Newborn Male Pregnancy Smoking / immunology |
| Chemical | |
Reg. No./Substance:
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37341-29-0/Immunoglobulin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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