| Total synthesis and absolute configuration of (-)-berkeleyamide A. | |
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MedLine Citation:
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PMID: 20030315 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A chiral-pool approach to (-)-berkeleyamide A 1 based on a diastereoselective nitrile oxide [3 + 2]-cycloaddition completes the first total synthesis establishing the absolute stereochemistry of the natural product. |
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Authors:
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Jonathan Sperry; Eric B J Harris; Margaret A Brimble |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Organic letters Volume: 12 ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-01-29 Completed Date: 2010-03-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
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Languages: eng Pagination: 420-3 Citation Subset: IM |
Affiliation:
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Department of Chemistry, University of Auckland, 23 Symonds Street, Auckland, New Zealand. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Products
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chemical synthesis*,
chemistry* Catalysis Cyclization Molecular Structure Penicillium / chemistry Pyrrolidinones / chemical synthesis*, chemistry* Stereoisomerism |
| Chemical | |
Reg. No./Substance:
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0/Biological Products; 0/Pyrrolidinones; 0/berkeleyamide A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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