Document Detail


Total enteral nutrition in prevention of pancreatic necrotic infection in severe acute pancreatitis.
MedLine Citation:
PMID:  19910834     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This study was designed to evaluate the effects of total enteral nutrition and total parenteral nutrition in prevention of pancreatic necrotic infection in severe acute pancreatitis. METHODS: One hundred seven patients were enrolled in the study between 2003 and 2007. In the first week of hospitalization, they were randomized to feeding by either total parenteral nutrition (54 patients) or total enteral nutrition (53 patients). All patients were concomitantly administered with sufficient prophylactic antibiotics. Computed tomographic scan and C-reactive protein level indicated a similar clinical severity in both groups. RESULTS: Eighty percent of the patients developed organ failure in the group with total parenteral nutrition, which was higher than that in the group with total enteral nutrition (21%). Eighty percent and 22% (P < 0.05) of the patients in the total parenteral nutrition and total enteral nutrition groups, respectively, underwent surgical intervention. The incidence of pancreatic septic necroses in the group with total enteral nutrition (23%) was lower than that in the group with total parenteral nutrition (72%, P < 0.05). Mortality in the total parenteral nutrition group (43%) was higher than in the total enteral nutrition group (11%, P < 0.05). CONCLUSION: Total enteral nutrition is better than total parenteral nutrition in the prevention of pancreatic necrotic infection in severe acute pancreatitis.
Authors:
Xing-Mao Wu; Kai-Qiang Ji; Hai-Yuan Wang; Guo-Fu Li; Bin Zang; Wei-Min Chen
Related Documents :
23245444 - The development of aortic insufficiency in continuous-flow left ventricular assist devi...
25086944 - Anterior tracheal suspension for tracheobronchomalacia in infants and children.
23916414 - Obstacle crossing following stroke improves over one month when the unaffected limb lea...
3140744 - Immune and metabolic effects of arginine in the surgical patient.
20492074 - Coronally advanced flap versus connective tissue graft in the treatment of multiple gin...
22915884 - Combined posterior lumbar plexus-sciatic nerve block versus combined femoral-obturator-...
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Pancreas     Volume:  39     ISSN:  1536-4828     ISO Abbreviation:  Pancreas     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-25     Completed Date:  2010-05-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8608542     Medline TA:  Pancreas     Country:  United States    
Other Details:
Languages:  eng     Pagination:  248-51     Citation Subset:  IM    
Affiliation:
Intensive Care Unit, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China. wuxingmao@sohu.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Bacterial Agents / therapeutic use
Bacterial Infections / microbiology,  mortality,  pathology,  prevention & control*
Biological Markers / blood
C-Reactive Protein / metabolism
Chi-Square Distribution
Enteral Nutrition* / adverse effects,  mortality
Female
Humans
Male
Middle Aged
Multiple Organ Failure / microbiology,  prevention & control
Pancreatitis, Acute Necrotizing / complications,  diagnosis,  mortality,  surgery,  therapy*
Parenteral Nutrition, Total* / adverse effects,  mortality
Pneumonia, Aspiration / microbiology,  prevention & control
Severity of Illness Index
Shock, Septic / microbiology,  prevention & control
Time Factors
Tomography, Spiral Computed
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Biological Markers; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hospital Volume as a Predictor for Undergoing Cholecystectomy After Admission for Acute Biliary Panc...
Next Document:  Robotic and Laparoscopic Pancreaticoduodenectomy: A Hybrid Approach.