| Total Cardiovascular Risk, Blood Pressure Variability and Adrenergic Overdrive in Hypertension: Evidence, Mechanisms and Clinical Implications. | |
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MedLine Citation:
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PMID: 22552574 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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In hypertensive patients the risk of developing cardiovascular events and complications depends not only on the magnitude of the blood pressure elevation, but also, and to a consistent extent, on the presence of associated cardiovascular risk factors, concomitant disease and target organ damage. Recent findings suggest that also sympathetic overdrive and alterations in blood pressure variability (which are detected in hypertension) may participate at the increased cardiovascular risk of the patients with high blood pressure. This review will discuss the evidence collected over the past few years on the relationships between sympathetic activation and blood pressure variability and their impact on cardiovascular risk profile. |
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Authors:
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Guido Grassi; Michele Bombelli; Gianmaria Brambilla; Fosca Quarti Trevano; Raffaella Dell'oro; Giuseppe Mancia |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-3 |
Journal Detail:
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Title: Current hypertension reports Volume: - ISSN: 1534-3111 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888982 Medline TA: Curr Hypertens Rep Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Clinica Medica, Ospedale San Gerardo dei Tintori Monza, University of Milano-Bicocca, Milan, Italy, guido.grassi@unimib.it. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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