| Torsade de pointes and other pause-induced ventricular tachycardias: the short-long-short sequence and early afterdepolarizations. | |
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MedLine Citation:
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PMID: 2456546 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The early afterdepolarization, which is an interruption of repolarization, can evoke a second upstroke or a salvo of action potentials. It is suggested that the electrophysiological characteristics of the early afterdepolarization can produce a lengthening of the QT interval and that the second upstroke and salvo of activity that may follow, it can explain many features of torsade de pointes and of certain other ventricular tachycardias. The early afterdepolarization, torsade de pointes, and repetitive monomorphic idiopathic ventricular tachycardia are all induced by bradycardia or by a preceding long RR interal. The R-on-T phenomenon is also discussed. |
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Authors:
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P F Cranefield; R S Aronson |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 11 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 1988 Jun |
Date Detail:
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Created Date: 1988-08-26 Completed Date: 1988-08-26 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 670-8 Citation Subset: IM |
Affiliation:
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Laboratory of Cardiac Physiology, Rockefeller University, New York, N.Y. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Dogs Electrocardiography Heart Conduction System / physiopathology* Humans Long QT Syndrome / physiopathology Tachycardia / physiopathology* Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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HL-14899/HL/NHLBI NIH HHS; HL-32688/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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