Document Detail


Torpor in lactating Siberian hamsters subjected to glucoprivation.
MedLine Citation:
PMID:  9458897     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Daily torpor has never been reported for any rodent species during lactation. To test whether torpor and lactation are incompatible processes, we administered 2-deoxy-D-glucose (2-DG), a glucose analog that interferes with cellular glycolysis, to Siberian hamsters during the 2nd wk postpartum. 2-DG (2,500 mg/kg of body mass) induced torpor in lactating as well as nonlactating females. Although depth of torpor did not differ between groups, duration of torpor tended to be shorter in lactating animals. Evidence of new milk bands suggests that pups were able to obtain milk from torpid dams. By contrast, dams subjected either to a combination of brief food deprivation and subsequent food restriction or just food restriction failed to display torpor, but instead cannibalized one or more pups. We conclude that torpor is possible during lactation; whether lactating dams in nature become torpid in response to energy shortages or cannibalize or abandon one or more of their offspring remains unknown.
Authors:
J L Stamper; I Zucker; D A Lewis; J Dark
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of physiology     Volume:  274     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-02-23     Completed Date:  1998-02-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  R46-51     Citation Subset:  IM    
Affiliation:
Department of Psychology, University of California, Berkeley 94720-1650, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Body Temperature Regulation / drug effects,  physiology*
Circadian Rhythm / physiology*
Cricetinae
Deoxyglucose / pharmacology*
Female
Glycolysis / drug effects,  physiology*
Lactation / physiology*
Phodopus
Postpartum Period / physiology
Sleep Stages
Grant Support
ID/Acronym/Agency:
NS-30816/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
154-17-6/Deoxyglucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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