Document Detail


Topology-Bayes versus Clade-Bayes in phylogenetic analysis.
MedLine Citation:
PMID:  18079139     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several features of currently used Bayesian methods in phylogenetic analysis are discussed. The distinction between Clade-Bayes and Topology-Bayes is presented and illustrated with an empirical example. Three problems with Bayesian phylogenetic methods--exaggerated clade support, inconsistently biased priors, and the impossibility of hypothesis testing of cladograms--are shown to be the result of using a Clade-based Bayesian approach. Topology-based Bayesian methods do not share these shortcomings.
Authors:
Ward C Wheeler; Kurt M Pickett
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Publication Detail:
Type:  Journal Article     Date:  2007-12-12
Journal Detail:
Title:  Molecular biology and evolution     Volume:  25     ISSN:  1537-1719     ISO Abbreviation:  Mol. Biol. Evol.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-06     Completed Date:  2008-05-19     Revised Date:  2009-02-03    
Medline Journal Info:
Nlm Unique ID:  8501455     Medline TA:  Mol Biol Evol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  447-53     Citation Subset:  IM    
Affiliation:
Division of Invertebrate Zoology, American Museum of Natural History, NY, USA. wheeler@amnh.org
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MeSH Terms
Descriptor/Qualifier:
Bayes Theorem
Evolution, Molecular*
Models, Genetic*
Phylogeny*
Comments/Corrections
Comment In:
Mol Biol Evol. 2009 Jan;26(1):1-3   [PMID:  18984901 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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