| Topographic variation and interocular symmetry of macular choroidal thickness using enhanced depth imaging optical coherence tomography. | |
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MedLine Citation:
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PMID: 22232433 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Purpose:To report and analyse factors influencing topographical and interocular variations of choroidal thickness (CT) in healthy adult population.Methods:100 eyes of 50 healthy subjects underwent visual acuity and axial length measurements and optical coherence tomography with enhanced depth imaging using the Heidelberg Spectralis HRA+OCT. CT at the fovea, and 3 mm nasal, temporal, superior and inferior to the fovea were measured manually. Topographic variation, relative interocular differences in CT and predictors of CT were analysed. The relationship between interocular differences in CT, age and interocular axial length differences was explored.Results:The mean (SD) foveal CT in the right and left eyes were 334 (95) and 333 (90) microns, respectively. For foveal CT (microns), there was high correlation between the 2 eyes (r = .90) with a relative interocular 95% limits of agreement of -80 to +83, and a median (range) absolute difference of 21 (0.4 to 135). There was no significant variation in the relative and absolute interocular differences in CT. Axial length was the main predictor of CT for nasal and foveal CT. Symmetry in CT in the horizontal and vertical meridians was seen in eyes with axial length shorter than 23.50 mm (p < .05).Conclusions:There was no significant relative interocular difference in CT. Axial length contributes to some of the variances in CT but has a significant influence on CT profile. Although relative interocular difference is not significant, absolute interocular differences in CT may reach 85 microns. |
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Authors:
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Fred K Chen; Jonathan Yeoh; Waheeda Rahman; Praveen J Patel; Adnan Tufail; Lyndon Da Cruz |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-9 |
Journal Detail:
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Title: Investigative ophthalmology & visual science Volume: - ISSN: 1552-5783 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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. Centre for Ophthalmology and Visual Science (incorporating Lions Eye Institute), University of Western Australia, Perth, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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