Document Detail


Topographic aspects of prostacyclin-like and fibrinolytic activity and of biogenic amines in the arterial system of the mini-pig.
MedLine Citation:
PMID:  3518249     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although arteriosclerosis is a systemic disease, it nevertheless exhibits noticeable topographical preference and particularities. The reason for this could be lie with certain biochemical features of the arterial wall. We therefore examined prostacyclin-like and fibrinolytic activity in mini-pigs, as well as the concentration of various biogenic amines in the thoracic and abdominal aorta, in coronary arteries and in the carotid and femoral artery. There was a similar behaviour between PG I2-like release and biogenic amines in the different arteries, whereas fibrinolytic activity behaved differently in some cases. In the femoral artery particularly low fibrinolytic activity was confronted by a particularly high level of PG I2-like activity and biogenic amines, while the reverse was the case in the abdominal aorta. In older animals PG I2-like activity considerably decreased.
Authors:
M Marshall; K U Weithmann; D Sacher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  98     ISSN:  0043-5325     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  1986 Apr 
Date Detail:
Created Date:  1986-06-09     Completed Date:  1986-06-09     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  AUSTRIA    
Other Details:
Languages:  eng     Pagination:  215-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Arteries / metabolism
Arteriosclerosis / blood*
Biogenic Amines / blood*
Dopamine / blood
Epoprostenol / blood*
Female
Fibrinolysis*
Male
Muscle, Smooth, Vascular / metabolism*
Norepinephrine / blood
Serotonin / blood
Swine
Swine, Miniature
Chemical
Reg. No./Substance:
0/Biogenic Amines; 35121-78-9/Epoprostenol; 50-67-9/Serotonin; 51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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