Document Detail


Topiramate responsive exploding head syndrome.
MedLine Citation:
PMID:  20726288     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exploding head syndrome is a rare phenomenon but can be a significant disruption to quality of life. We describe a 39-year-old female with symptoms of a loud bang and buzz at sleep onset for 3 years. EEG monitoring confirmed these events occurred in transition from stage 1 sleep. This patient reported improvement in intensity of events with topiramate medication. Based on these results, topiramate may be an alternative method to reduce the intensity of events in exploding head syndrome.
Authors:
Gaurang M Palikh; Bradley V Vaughn
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine     Volume:  6     ISSN:  1550-9389     ISO Abbreviation:  J Clin Sleep Med     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-23     Completed Date:  2010-09-16     Revised Date:  2011-07-25    
Medline Journal Info:
Nlm Unique ID:  101231977     Medline TA:  J Clin Sleep Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  382-3     Citation Subset:  IM    
Affiliation:
Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7025, USA. patelg@neurology.unc.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Anticonvulsants / therapeutic use*
Auditory Perceptual Disorders / diagnosis,  drug therapy*
Dose-Response Relationship, Drug
Female
Fructose / analogs & derivatives*,  therapeutic use
Humans
Illusions*
Migraine with Aura / diagnosis,  drug therapy*
Polysomnography
Sleep-Wake Transition Disorders / diagnosis,  drug therapy*
Chemical
Reg. No./Substance:
0/Anticonvulsants; 30237-26-4/Fructose; 97240-79-4/topiramate
Comments/Corrections

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