| Topiramate related reversible erectile dysfunction in temporal lobe epilepsy. | |
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MedLine Citation:
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PMID: 21744107 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Topiramate (TPM) is a newer antiepileptic drug with high efficacy in treating various neurological disorders, especially epilepsy and migraine. The adverse effects of TPM therapy are mainly central nervous system-related somnolence and dizziness. There are rare reports about the role of TPM on sexual effects, but with inconsistent results. In this report, we describe a 31-year-old man who developed erectile dysfunction after several months of TPM use. Complete urological and sexual psychiatric evaluations were done. There was lack of an identifiable organic basis and psychiatric pathology in this patient. The erectile dysfunction improved only after the termination of TPM, documenting the temporal relationship. We reviewed and discussed the clinical aspect of TPM use in erectile dysfunction. This case and the rare cases of erectile dysfunction in TPM use reported in the literature show that TPM is worth to be paid attention to whenever it is prescribed in a wide range of neurological disorders. |
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Authors:
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Ling-Chien Hung; Julie Chi Chow; Chia-Yen Chang; Jing-Jane Tsai; Chin-Wei Huang |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-9 |
Journal Detail:
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Title: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology Volume: - ISSN: 1590-3478 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100959175 Medline TA: Neurol Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Neurology, National Cheng Kung University Hospital, 138 Sheng-Li Road, Tainan, 704, Taiwan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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