| Topical vitamin D3 (tacalcitol) for steroid-resistant prurigo. | |
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MedLine Citation:
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PMID: 8881666 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A topical vitamin D3 ointment (tacalcitol) was prescribed for patients with long-lasting pruriginous lesions (four with prurigo nodularis and seven with subacute prurigo, four of whom had atopic dermatitis). Seven of 11 cases had not responded to a topical steroid ointment and even to occlusive application of the ointment. Nine of 11 cases showed a significant clinical response to this new regimen within 4 weeks. Epidermal Fc epsilon R1(+) dendritic cells were increased in number in prurigo nodularis and reduced to normal level after the therapy. Topical vitamin D3 ointment might be an alternative therapy for steroid-resistant prurigo. |
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Authors:
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I Katayama; Y Miyazaki; K Nishioka |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of dermatology Volume: 135 ISSN: 0007-0963 ISO Abbreviation: Br. J. Dermatol. Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1996-12-16 Completed Date: 1996-12-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0004041 Medline TA: Br J Dermatol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 237-40 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Tokyo Medical and Dental University School of Medicine, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Adult Aged Cell Adhesion Molecules / analysis Cholecalciferol / administration & dosage, therapeutic use* Drug Resistance Female Humans Immunohistochemistry Male Middle Aged Prurigo / drug therapy* Skin / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Cell Adhesion Molecules; 67-97-0/Cholecalciferol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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