Document Detail

Topical negative pressure therapy: current concepts and practice.
MedLine Citation:
PMID:  23162996     Owner:  NLM     Status:  In-Process    
Research into topical negative pressure therapy (TNPT) started in 1989 with Dr Louis Argenta and Prof Michael Morykwas of Wake Forest University School of Medicine in North Carolina, USA. In 1997, Morykwas and Argenta concluded that TNPT both enhanced granulation tissue formation and helped bacterial clearance, through the actions of negative pressure Armstrong and Lavery confirmed this in 2005, concluding that TNPT therapy was promoting the development of granulation tissue. Numerous other studies have proved that TNPT is beneficial for a myriad of other wounds including: sternotomy wounds, extensive de-gloving injuries, various soft tissue injuries prior to surgical closure, skin grafting, pressure sores, leg ulcers, sacral pressure ulcers, acute traumatic soft tissue defects, and soft tissue defects following rigid stabilisation of lower extremity fractures. This review aims to summarise the clinical and scientific concepts of TNPT and its future applications.
M Malahias; S Hindocha; F Saedi; P McArthur
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perioperative practice     Volume:  22     ISSN:  1750-4589     ISO Abbreviation:  J Perioper Pract     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-11-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101271023     Medline TA:  J Perioper Pract     Country:  England    
Other Details:
Languages:  eng     Pagination:  328-32     Citation Subset:  N    
Good Hope Hospital, West Midlands.
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